Splenomegaly with Anæmia and Hæmorrhages

Splenomegaly, hypersplenism, and hereditary disorders with splenomegaly

Splenomegaly, sometimes of massive extent, occurs in a large number of hereditary diseases, some relatively prevalent and others, rare to ultra-rare. Because physicians are often unfamiliar with the less common disorders, patients may suffer because of diagnostic delay or diagnostic error and may undergo invasive, non-innocuous procedures such as splenectomy that are potentially avoidable were ...

Anæmia in Practice: Pernicious Anæmia

Thirteen years ago, Drs. G. R. Minot and W. P. Murphy published a paper in the Journal of the American Medical Association describing the effect of liver diet in pernicious anaemia. This was a clinical study, but the results were striking enough to attract a considerable amount of attention, not only of clinicians but of laboratory workers as well. The immediate direct result was a revolutionar...

Anæmia Treated with Milk

He stated that since October, 1847, he had suffered constantly from diarrhoea, that his motions were light coloured and watery, and that he was rarely moved less frequently than 10 times daily. He was admitted into the General Hospital on the 12th of December, 18(39. Then his motions were abundant, light coloured, and watery; he was anaemic, emaciated, and exceedingly feeble. He was put on a pu...

A Case of Multiple Hæmorrhages

Condition on admissionT-98.4?F., P-92, R-16. General condition, good and constitutional disturbances, nil. Sallow complexion. Eyes, normal. Tongue, neither furred nor swollen but haemorrhages present both at the tip and the base, consisting of circular patches about one-third of an inch in diameter. These haemorrhages had partially clotted but on removing the clot oozing continued. Gums not spo...

Achlorhydria and Anæmia